About Us

Myrobalan - Harnessing the restorative
potential of novel CNS therapeutics

Myrobalan Therapeutics is a CNS-focused pre-clinical biotech company developing medicines to address the unmet need and societal burdens of neurodegenerative and demyelinating disorders. We focus our efforts on targeting specialized cells in the CNS, such as microglia and oligodendrocytes, which play crucial roles in maintaining nervous system health and function. We are committed to transforming the future for patients with neurological diseases through the development of safe and effective precision medicines that restore brain health under the guidance of biomarkers.

Our goal is to restore brain function by addressing critical disease mechanisms common to major CNS disorders. Our potentially first-in-class and best-in-class small molecule CNS therapies promote remyelination and address neuroinflammation to combat neurological diseases such as multiple sclerosis, Alzheimer's disease, ALS, Parkinson's disease, and other demyelinating and neurodegenerative disorders.

Our Scientific Founders

The deep scientific foundation behind Myrobalan's areas of focus has accelerated the development of its promising pipeline. Through a concerted and focused effort, we hope to make a positive impact for patients living with devastating neurological diseases.

Robust Foundations: Myrobalan's pioneering approach to CNS therapeutics is rooted in the groundbreaking research of our scientific co-founders:

Dr. Zhigang He: A globally recognized leader in axon-regeneration and neurodegeneration, Dr. He and the He Laboratory at the FM Kirby Neurobiology Center at Boston Children's Hospital/Harvard Medical School focus on neural repair and rebuilding neural circuitry after injury. Dr. He is a Harvard Professor of Neurology and a member of the National Academy of Medicine.

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Dr. Guoping Feng: An internationally renowned expert in synapse and circuit dysfunction, Dr. Feng leads the Feng Laboratory at MIT/Broad Institute, investigating the role of these mechanisms in brain disorders. He is an MIT Professor, Institute Member of the Broad Institute, and a dual member of the National Academy of Sciences and National Academy of Medicine.

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Their innovative work on demyelination and neuroinflammation has led Myrobalan to pursue these fundamental mechanisms to CNS disorders.

Myrobalan's namesake

Myrobalan is a plant held by the Medicine Buddha whenever he is pictured. According to Tibetan Buddhism tradition, Myrobalan is regarded as the only herb capable of healing illnesses that have their root cause in conflicting emotions.